The new topical gel that blocks the receptor for a molecule called succinate treats periodontitis — also known as gum disease or periodontal disease — by suppressing inflammation and changing the makeup of bacteria in the mouth, according to new research. Guo et al. reveal succinate’s effect on periodontitis pathogenesis and provides a topical treatment for this disease. Image credit: Guo et al., doi: 10.1016/j.celrep.2022.111389. “No...
